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Use of buffered lidocaine did not provide better pain control than unbuffered...

A 2010 Cochrane review (Cepeda et al) found that there was less pain associated with pain on injection and augmented patient comfort and satisfaction with the use of buffered lidocaine compared with...

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Lidocaine: trial suggests that buffering may not improve success of inferior...

Lidocaine one of the most commonly used local anaesthetics tends to have a low pH range. It has been suggested that buffering (alkalinisation) may reduce pain and some but not all studies has supported...

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Buffering local anaesthetics to reduce dental injection pain?

14 RCTs were included in this review of the effect of buffering local anaesthetics in reducing infiltration pain and anaesthesia onset time in dentistry. While slight reductions in onset time was seen...

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